Overview of HBV associated Fulminant hepatitis B

Fulminant hepatitis or massive hepatic cell death, is a rare and life-threatening complication of acute hepatitis that can occur in cases of hepatitis B, D, and E, in addition to drug-induced and autoimmune hepatitis.The complication more frequently occurs in instances of hepatitis B and D co-infection at a rate of 2–20% and in pregnant women with hepatitis E at rate of 15–20% of cases. In addition to the signs of acute hepatitis, people can also demonstrate signs of coagulopathy (abnormal coagulation studies with easy bruising and bleeding) and encephalopathy (confusion, disorientation, and sleepiness). In addition to the signs of acute hepatitis, people can also demonstrate signs of coagulopathy (abnormal coagulation studies with easy bruising and bleeding) and encephalopathy (confusion, disorientation, and sleepiness).

ID	Literature	Title	Group
1	22720023	Hepatitis B virus gene mutations in liver diseases: a report from New Delhi.	Mutation
2	33857724	LCR based quick detection of hotspot G1896A mutation in patients with different spectrum of hepatitis B.	Mutation
3	9425945	Hepatitis B virus with antigenically altered hepatitis B surface antigen is selected by high-dose hepatitis B immune globulin after liver transplantation.	Mutation
4	9303514	Surface gene mutants of hepatitis B virus in infants who develop acute or chronic infections despite immunoprophylaxis.	Mutation
5	30505167	Hepatitis B virus precore G1896A mutation in chronic liver disease patients with HBeAg negative serology from North India.	Mutation
6	25132075	Molecular analysis of the interspousal transmission of hepatitis B virus in two Japanese patients who acquired fulminant hepatitis B after 50 and 49 years of marriage.	Mutation
7	23773581	Renal transplantation from hepatitis B surface antigen (HBsAg)-positive donors to HBsAg-negative recipients: a case of post-transplant fulminant hepatitis associated with an extensively mutated hepatitis B virus strain and review of the current literature.	Mutation
8	23596461	Drug-related mutational patterns in hepatitis B virus (HBV) reverse transcriptase proteins from Iranian treatment-naïve chronic HBV patients.	Mutation
9	22795596	Association between S21 substitution in the core protein of hepatitis B virus and fulminant hepatitis.	Mutation
10	10745228	Properties of hepatitis B virus genome recovered from Vietnamese patients with fulminant hepatitis in comparison with those of acute hepatitis.	Mutation
11	22037043	Fatal fulminant primary hepatitis B virus infections with G1896A precore viral mutants in southeastern France.	Mutation
12	19850315	Enhanced intracellular retention of a hepatitis B virus strain associated with fulminant hepatitis.	Mutation
13	18428142	Analysis of the entire nucleotide sequence of hepatitis B causing consecutive cases of fatal fulminant hepatitis in Miyagi Prefecture Japan.	Mutation
14	17498766	Influences on hepatitis B virus replication by a naturally occurring mutation in the core gene.	Mutation
15	12185284	Detection and significance of a G1862T variant of hepatitis B virus in Chinese patients with fulminant hepatitis.	Mutation
16	11596083	Molecular analysis of hepatitis B virus genomes isolated from black African patients with fulminant hepatitis B.	Mutation
17	11481624	A dominant hepatitis B virus population defective in virus secretion because of several S-gene mutations from a patient with fulminant hepatitis.	Mutation

Contents
Description

Group Note

Mutation Tag: literature about this virus mutation and click the eye icon to see detail mutation information in literature
VIS-cistrome Tag: literature associated this virus integration and click the eye icon to see detail information of 3 cistrome factors (histone modification, transcription factor binding site and chromatin accessibility)