Home
Virus
Gene
Disease
Dataset
Download
Help
 
Overview of HBV associated Liver cirrhosis

Liver cirrhosis is a condition in which the liver does not function properly due to long-term damage.This damage is characterized by the replacement of normal liver tissue by scar tissue.Typically, the disease develops slowly over months or years [1]. Early on, there are often no symptoms.As the disease worsens, a person may become tired, weak, itchy, have swelling in the lower legs, develop yellow skin, bruise easily, have fluid buildup in the abdomen, or develop spider-like blood vessels on the skin.


ID Literature Title Group
1 30406036 The Correlation Between Hepatitis B Virus Precore/Core Mutations and the Progression of Severe Liver Disease.
Mutation
2 23596461 Drug-related mutational patterns in hepatitis B virus (HBV) reverse transcriptase proteins from Iranian treatment-naïve chronic HBV patients.
Mutation
3 23903686 Hepatitis B virus subgenotype C2- and B2-associated mutation patterns may be responsible for liver cirrhosis and hepatocellular carcinoma, respectively.
Mutation
4 24637457 Mutation profiling of the hepatitis B virus strains circulating in North Indian population.
Mutation
5 24763132 Higher proportion of viral basal core promoter mutant increases the risk of liver cirrhosis in hepatitis B carriers.
Mutation
6 25281206 Impacts of human leukocyte antigen DQ genetic polymorphisms and their interactions with hepatitis B virus mutations on the risks of viral persistence, liver cirrhosis, and hepatocellular carcinoma.
Mutation
7 25333524 Novel point and combo-mutations in the genome of hepatitis B virus-genotype D: characterization and impact on liver disease progression to hepatocellular carcinoma.
Mutation
8 26577140 Hepatitis B virus basal core promoter/precore mutants and association with liver cirrhosis in children with chronic hepatitis B virus infection.
Mutation
9 26899956 Molecular characterization of hepatitis B virus from chronically-infected patients in Niamey, Niger.
Mutation
10 27486882 Occult HBV infection in HCC and cirrhotic tissue of HBsAg-negative patients: a virological and clinical study.
Mutation
11 28373061 Sequence analysis and functional characterization of full-length hepatitis B virus genomes from Korean cirrhotic patients with or without liver cancer.
Mutation
12 28902288 Basal core promoter and precore mutations among hepatitis B virus circulating in Brazil and its association with severe forms of hepatic diseases.
Mutation
13 29285238 Hepatitis B virus (HBV) X gene mutations and their association with liver disease progression in HBV-infected patients.
Mutation
14 23304671 HBV Subgenotype C2 Infection, A1762T/G1764A Mutations May Contribute To Hepatocellular Carcinoma with Cirrhosis in Southeast China.
Mutation
15 30505167 Hepatitis B virus precore G1896A mutation in chronic liver disease patients with HBeAg negative serology from North India.
Mutation
16 31105017 Association of HBsAg mutation patterns with hepatitis B infection outcome: Asymptomatic carriers versus HCC/cirrhotic patients.
Mutation
17 31308922 Nucleotide Substitutions in Hepatitis B Viruses Derived from Chronic HBV Patients.
Mutation
18 31341154 Association Between HBx Variations and Development of Severe Liver Disease Among Indonesian Patients.
Mutation
19 31501793 Comparison of pre-S1/S2 variations of hepatitis B virus between asymptomatic carriers and cirrhotic/hepatocellular carcinoma-affected individuals.
Mutation
20 31565220 Association between host TNF-α, TGF-β1, p53 polymorphisms, HBV X gene mutation, HBV viral load and the progression of HBV-associated chronic liver disease in Indonesian patients.
Mutation
21 32155009 [The prevalence clinically significant virus mutations among patients with chronic viral hepatitis B.]
Mutation
22 32523313 Conservation and variability of hepatitis B core at different chronic hepatitis stages.
Mutation
23 32568442 The genetic polymorphism down-regulating HLA-DRB1 enhancer activity facilitates HBV persistence, evolution and hepatocarcinogenesis in the Chinese Han population.
Mutation
24 9425945 Hepatitis B virus with antigenically altered hepatitis B surface antigen is selected by high-dose hepatitis B immune globulin after liver transplantation.
Mutation
25 33857724 LCR based quick detection of hotspot G1896A mutation in patients with different spectrum of hepatitis B.
Mutation
26 33947693 The Landscape of Cell-Free HBV Integrations and Mutations in Cirrhosis and Hepatocellular Carcinoma Patients.
Mutation
27 20087936 Molecular evolutionary analysis and mutational pattern of full-length genomes of hepatitis B virus isolated from Belgian patients with different clinical manifestations.
Mutation
28 12436473 Hepatitis B virus S gene mutants in a patient with chronic active hepatitis with circulating Anti-HBs antibodies.
Mutation
29 15048802 Fibrosing cholestatic hepatitis secondary to precore/core promoter hepatitis B variant with lamivudine resistance: successful retransplantation with combination adefovir dipivoxil and hepatitis B immunoglobulin.
Mutation
30 15338371 Prognostic indicators of breakthrough hepatitis during lamivudine monotherapy for chronic hepatitis B virus infection.
Mutation
31 16618410 High prevalence and mapping of pre-S deletion in hepatitis B virus carriers with progressive liver diseases.
Mutation
32 17030194 Selection of a multiple drug-resistant hepatitis B virus strain in a liver-transplanted patient.
Mutation
33 17203204 Genotype and variations in core promoter and pre-core regions are related to progression of disease in HBV-infected patients from Northern Vietnam.
Mutation
34 17239478 Stepwise process for the development of entecavir resistance in a chronic hepatitis B virus infected patient.
Mutation
35 17259736 G1862T mutation among hepatitis B virus-infected individuals: association with viral genotypes and disease outcome in Kolkata, Eastern India.
Mutation
36 18507754 Clinical significance of precore and core promoter mutations in genotype D hepatitis B-related chronic liver disease.
Mutation
37 18508941 Application of a novel, rapid, and sensitive oligonucleotide ligation assay for detection of cancer-predicting mutations in the precore and basal core promoter of hepatitis B virus.
Mutation
38 18551606 Hepatitis B virus X mutations occurring naturally associated with clinical severity of liver disease among Korean patients with chronic genotype C infection.
Mutation
39 19008175 Core promoter mutant HBV non-responding to adefovir after viral breakthrough on lamivudine: rapid virologic response to tenofovir plus lamivudine in a cirrhotic patient.
Mutation
40 10320044 Hepatitis B virus variants with lamivudine-related mutations in the DNA polymerase and the 'a' epitope of the surface antigen are sensitive to ganciclovir.
Mutation
41 20119580 Hepatitis B viral surface mutations in patients with adefovir resistant chronic hepatitis B with A181T/V polymerase mutations.
Mutation
42 20419326 Significant association of different preS mutations with hepatitis B-related cirrhosis or hepatocellular carcinoma.
Mutation
43 20559531 A YIDD Mutation in a Case of Recurrent Hepatitis B after Liver Transplantation Induced by an S-escape Mutant.
Mutation
44 20959817 Association between the various mutations in viral core promoter region to different stages of hepatitis B, ranging of asymptomatic carrier state to hepatocellular carcinoma.
Mutation
45 21159112 Prevention of lamivudine-resistant hepatitis B recurrence after liver transplantation with entecavir plus tenofovir combination therapy and perioperative hepatitis B immunoglobulin only.
Mutation
46 21392168 Genotypic resistance profile of hepatitis B virus (HBV) in a large cohort of nucleos(t)ide analogue-experienced Chinese patients with chronic HBV infection.
Mutation
47 21863638 [One-year combination therapy de novo of adefovir dipivoxil and lamivudine for decompensated cirrhosis related to HBV].
Mutation
48 21941645 Etiology and Viral Genotype in Patients with End-Stage Liver Diseases admitted to a Hepatology Unit in Colombia.
Mutation
49 22313146 Reactivation of hepatitis B virus with mutated hepatitis B surface antigen in a liver transplant recipient receiving a graft from an antibody to hepatitis B surface antigen- and antibody to hepatitis B core antigen-positive donor.
Mutation
50 22720023 Hepatitis B virus gene mutations in liver diseases: a report from New Delhi.
Mutation
51 22919746 [Hepatitis B virus (HBV) mutation in enhancer I (HBV Enh I)/X-promoter and the relationship between chronic HBV-related disease spectrum].
Mutation
Contents
Description
Group Note
  • Mutation Tag: literature about this virus mutation and click the eye icon to see detail mutation information in literature
  • VIS-cistrome Tag: literature associated this virus integration and click the eye icon to see detail information of 3 cistrome factors (histone modification, transcription factor binding site and chromatin accessibility)