Overview of HPV associated
ID Literature Title Group
1 29630659 STAT3 activation by E6 is essential for the differentiation-dependent HPV18 life cycle.
Mutation
2 31426742 In silico prediction of structural changes in human papillomavirus type 16 (HPV16) E6 oncoprotein and its variants.
Mutation
3 30875834 The Protein Tyrosine Phosphatase H1 PTPH1 Supports Proliferation of Keratinocytes and is a Target of the Human Papillomavirus Type 8 E6 Oncogene.
Mutation
4 30842331 Phosphorylation of a Conserved Tyrosine in the Papillomavirus E2 Protein Regulates Brd4 Binding and Viral Replication.
Mutation
5 30676312 Oncogenicitiy Comparison of Human Papillomavirus Type 52 E6 Variants.
Mutation
6 30575267 Oncogenic comparison of human papillomavirus type 58 E7 variants.
Mutation
7 30322153 HPV-18 E6 Oncoprotein and Its Spliced Isoform E6*I Regulate the Wnt/β-Catenin Cell Signaling Pathway through the TCF-4 Transcriptional Factor.
Mutation
8 29893470 CIP2A facilitates the G1/S cell cycle transition via B-Myb in human papillomavirus 16 oncoprotein E6-expressing cells.
Mutation
9 29643933 Human papillomavirus genome variants and head and neck cancers: a perspective.
Mutation
10 31708575 Human papillomavirus as a driver of head and neck cancers.
Mutation
11 29142126 Human Papillomavirus Replication Regulation by Acetylation of a Conserved Lysine in the E2 Protein.
Mutation
12 28968823 Naturally Occurring Single Amino Acid Substitution in the L1 Major Capsid Protein of Human Papillomavirus Type 16: Alteration of Susceptibility to Antibody-Mediated Neutralization.
Mutation
13 28794033 Ancient Evolution and Dispersion of Human Papillomavirus 58 Variants.
Mutation
14 28497579 Modulation of basal cell fate during productive and transforming HPV-16 infection is mediated by progressive E6-driven depletion of Notch.
Mutation
15 27829177 A naturally occurring variant of HPV-16 E7 exerts increased transforming activity through acquisition of an additional phospho-acceptor site.
Mutation
16 27806689 Functional variants of human papillomavirus type 16 demonstrate host genome integration and transcriptional alterations corresponding to their unique cancer epidemiology.
Mutation
17 27030265 The Human Papillomavirus 16 E7 Oncoprotein Attenuates AKT Signaling To Promote Internal Ribosome Entry Site-Dependent Translation and Expression of c-MYC.
Mutation
18 26732286 Enhanced expression of soluble human papillomavirus L1 through coexpression of molecular chaperonin in Escherichia coli.
Mutation
19 31915229 Human Papillomavirus 16 E6 and E7 Synergistically Repress Innate Immune Gene Transcription.
Mutation
20 31996427 Human Papillomavirus 58 E7 T20I/G63S Variant Isolated from an East Asian Population Possesses High Oncogenicity.
Mutation
21 32183180 Suppression of a Subset of Interferon-Induced Genes by Human Papillomavirus Type 16 E7 via a Cyclin Dependent Kinase 8-Dependent Mechanism.
Mutation
22 32304786 HPV16 L1 diversity and its potential impact on the vaccination-induced immunity.
Mutation
23 32350070 Phosphorylation of the Human Papillomavirus E2 Protein at Tyrosine 138 Regulates Episomal Replication.
Mutation
24 32435064 The possible regions to design Human Papilloma Viruses vaccine in Iranian L1 protein.
Mutation
25 32493825 Human Papillomavirus 31 Tyrosine 102 Regulates Interaction with E2 Binding Partners and Episomal Maintenance.
Mutation
26 32503989 Rational design of a multi-valent human papillomavirus vaccine by capsomere-hybrid co-assembly of virus-like particles.
Mutation
27 33155930 Human Papillomavirus E7 Oncoprotein Promotes Proliferation and Migration through the Transcription Factor E2F1 in Cervical Cancer Cells.
Mutation
28 33374731 High Risk α-HPV E6 Impairs Translesion Synthesis by Blocking POLη Induction.
Mutation
29 8627680 Targeted mutagenesis of the human papillomavirus type 16 E2 transactivation domain reveals separable transcriptional activation and DNA replication functions.
Mutation
30 9223484 Two classes of human papillomavirus type 16 E1 mutants suggest pleiotropic conformational constraints affecting E1 multimerization, E2 interaction, and interaction with cellular proteins.
Mutation
31 9733858 A fifteen-amino-acid peptide inhibits human papillomavirus E1-E2 interaction and human papillomavirus DNA replication in vitro.
Mutation
32 33573298 Modeling and Molecular Dynamics of the 3D Structure of the HPV16 E7 Protein and Its Variants.
Mutation
33 33636291 Worldwide genetic variations in high-risk human papillomaviruses capsid L1 gene and their impact on vaccine efficiency.
Mutation
34 18986660 Human papillomavirus 16 E6 variants differ in their dysregulation of human keratinocyte differentiation and apoptosis.
Mutation
35 10639310 HPV11 mutant virus-like particles elicit immune responses that neutralize virus and delineate a novel neutralizing domain.
Mutation
36 11336560 Induction of type-specific neutralizing antibodies by capsomeres of human papillomavirus type 33.
Mutation
37 11543887 Determination of the binding affinity of different human papillomavirus E7 proteins for the tumour suppressor pRb by a plate-binding assay.
Mutation
38 12196821 [Modification of HPV type 16 E6 and E7 genes, and analysis of stability and immunogenicity of the modified proteins].
Mutation
39 12239337 Inactivation of both the retinoblastoma tumor suppressor and p21 by the human papillomavirus type 16 E7 oncoprotein is necessary to inhibit cell cycle arrest in human epithelial cells.
Mutation
40 12551970 Nuclear entry of high-risk human papillomavirus type 16 E6 oncoprotein occurs via several pathways.
Mutation
41 12565157 DNA replicative functions of highly-expressed, codon-optimized human papillomavirus proteins E1 and E2.
Mutation
42 15767402 Human papillomavirus type 16 E1 E4-induced G2 arrest is associated with cytoplasmic retention of active Cdk1/cyclin B1 complexes.
Mutation
43 16519914 HPV16 E6 natural variants exhibit different activities in functional assays relevant to the carcinogenic potential of E6.
Mutation
44 16800784 The human papillomavirus type 16 E7 protein binds human interferon regulatory factor-9 via a novel PEST domain required for transformation.
Mutation
45 16938363 A deletion and point mutation study of the human papillomavirus type 16 major capsid gene.
Mutation
46 17048111 New HPV-16 European and non-European variants in Central Brazil.
Mutation
47 17452980 hAda3 regulates p14ARF-induced p53 acetylation and senescence.
Mutation
48 17854024 Activities of human papillomavirus 16 E6 natural variants in human keratinocytes.
Mutation
49 18619639 Modification of papillomavirus E2 proteins by the small ubiquitin-like modifier family members (SUMOs).
Mutation
50 10400710 The human papillomavirus type 16 E6 oncoprotein can down-regulate p53 activity by targeting the transcriptional coactivator CBP/p300.
Mutation
51 19015633 A single-codon mutation converts HPV16 E6 oncoprotein into a potential tumor suppressor, which induces p53-dependent senescence of HPV-positive HeLa cervical cancer cells.
Mutation
52 19214230 Two highly conserved cysteine residues in HPV16 L2 form an intramolecular disulfide bond and are critical for infectivity in human keratinocytes.
Mutation
53 20383192 The immortalizing and transforming ability of two common human papillomavirus 16 E6 variants with different prevalences in cervical cancer.
Mutation
54 20572344 [The enhancement of DNA binding ability of a mutated E2 (A338V) protein of HPV-2].
Mutation
55 21672450 Is there a biological plausability for p53 codon 72 polymorphism influence on cervical cancer development?
Mutation
56 21811610 Differentiation-dependent interpentameric disulfide bond stabilizes native human papillomavirus type 16.
Mutation
57 22333459 A point mutation in the DNA-binding domain of HPV-2 E2 protein increases its DNA-binding capacity and reverses its transcriptional regulatory activity on the viral early promoter.
Mutation
58 22571619 Human papillomavirus type 58: the unique role in cervical cancers in East Asia.
Mutation
59 24456830 Replication interference between human papillomavirus types 16 and 18 mediated by heterologous E1 helicases.
Mutation
60 24918586 Roles for human papillomavirus type 16 l1 cysteine residues 161, 229, and 379 in genome encapsidation and capsid stability.
Mutation
61 24928042 The nuclear retention signal of HPV16 L2 protein is essential for incoming viral genome to transverse the trans-Golgi network.
Mutation
62 25096873 Maturation of the human papillomavirus 16 capsid.
Mutation
63 25227848 A novel mutant of human papillomavirus type 18 E6E7 fusion gene and its transforming activity.
Mutation
64 25735347 Mutation detection of E6 and LCR genes from HPV 16 associated with carcinogenesis.
Mutation
65 26318249 The human papillomavirus 16 European-T350G E6 variant can immortalize but not transform keratinocytes in the absence of E7.
Mutation
Contents
Description
Group Note
  • Mutation Tag: literature about this virus mutation and click the eye icon to see detail mutation information in literature
  • VIS-cistrome Tag: literature associated this virus integration and click the eye icon to see detail information of 3 cistrome factors (histone modification, transcription factor binding site and chromatin accessibility)