|
DVID
|
1100058 |
|
Chromosome
|
chr10 |
|
GRCh38 Location
|
51769849, 51769877 |
|
Disease
|
Hepatocellular carcinoma |
|
Sample
|
Cell line |
|
Virus Reference Genome
|
X72702 |
|
Target Gene
|
PRKG1 |
Literature Information
|
PubMed PMID
|
31064734
|
|
Published year
|
2019 |
|
Journal
|
Cancer genetics |
|
Title
|
Retrotransposon elements among initial sites of hepatitis B virus integration into human genome in the HepG2-NTCP cell infection model. |
|
Author
|
Chauhan R,Shimizu Y,Watashi K,Wakita T,Fukasawa M,Michalak TI |
|
Evidence
|
At one-hour p.i., HBV integration with retrotransposon THE-1B-LTR was identified, while virus insertions into proline-rich protein and protein kinase cGMP-dependent type 1 encoding genes were found at 3 h p.i. Fusion with runt-related transcription factor 1 was detected at 24 h p.i. and merges with 9 different genes at 13 day p.i.
|
|
|
HBV VIS Detail Information