Literature Information
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PubMed PMID
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30016933
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Published year
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2018 |
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Journal
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BMC bioinformatics |
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Title
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HGT-ID: an efficient and sensitive workflow to detect human-viral insertion sites using next-generation sequencing data. |
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Author
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Baheti S,Tang X,O'Brien DR,Chia N,Roberts LR,Nelson H,Boughey JC,Wang L,Goetz MP,Kocher JA,Kalari KR |
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Evidence
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We applied HGT-ID to The Cancer Genome Atlas (TCGA) whole-genome sequencing data (WGS) from liver tumor-normal pairs. Multiple hepatitis B virus (HBV) integration sites were identified in TCGA liver samples and confirmed by HGT-ID using the RNA-Seq data from the matched liver pairs.
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