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Mutation Information
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Mutation Site
|
A131C |
|
Mutation Type
|
Nucleotide level |
|
Gene/Protein/Region Type
|
E6 |
|
Nucleotide_Mutation
|
R10R |
|
Genotype/Subtype
|
HPV16 |
|
Viral Reference
|
HQ644251.1
|
|
Country
|
China |
Literature Information
|
PubMed PMID
|
30981880
|
|
Disease
|
Cervical carcinoma
|
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Published Year
|
2019 |
|
Journal
|
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases |
|
Title
|
Human papillomavirus type 16 E6 and E7 gene variations associated with cervical cancer in a Han Chinese population. |
|
Author
|
Zhou Z,Yang H,Yang L,Yao Y,Dai S,Shi L,Li C,Yang L,Yan Z,Yao Y |
|
Evidence
|
When the distribution of the HPV16 E6 and E7 gene variations was compared, the distribution of only A131C (R10R) in the E6 gene showed a different trend between the case and control groups and C749T (S63F) in the E7 gene was significantly different between the case and control groups (P = 0.071 and P = 4.861 x 10-10, respectively).
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HPV Mutation Detail Information