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Mutation Information
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Mutation Site
|
A146T |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
Gag |
|
Viral Reference
|
NC001802
|
|
Immune Escape
|
Y |
|
Country
|
Brazil |
Literature Information
|
PubMed PMID
|
32711474
|
|
Disease
|
HIV infection/AIDS
|
|
Published Year
|
2020 |
|
Journal
|
BMC infectious diseases |
|
Title
|
Immune escape mutations in HIV-1 controllers in the Brazilian Amazon region. |
|
Author
|
Gomes STM,da Silva Graça Amoras E,Gomes ÉR,Queiroz MAF,Júnior ECS,de Vasconcelos Massafra JM,da Silva Lemos P,Júnior JLV,Ishak R,Vallinoto ACR |
|
Evidence
|
In addition, two new mutations were identified, namely, a substitution from alanine to threonine at position 146 of the p24 protein (A146T;Fig. 2) in two individuals from the VC group and a phenylalanine substitution to leucine at position 383 of the p7 protein (F383L) in the NVC group.
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