|
Mutation Information
|
Mutation Site
|
A159V |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
S |
|
Viral Reference
|
AY161159D1;
AB073823B2;
D0032981;
AY217378C1;
Y1885C2;
M12906C2 |
|
Immune Escape
|
Y |
|
Relevant Drug
|
lamivudine (LAM);entecavir (ETV) |
|
Country
|
china |
Literature Information
|
PubMed PMID
|
32994690
|
|
Disease
|
Chronic hepatitis B
|
|
Published Year
|
2020 |
|
Journal
|
World journal of gastroenterology |
|
Title
|
Investigation of immune escape-associated mutations of hepatitis B virus in patients harboring hepatitis B virus drug-resistance mutations. |
|
Author
|
Huang BX,Liu Y,Fan ZP,Si LL,Chen RJ,Wang J,Luo D,Wang FS,Xu DP,Liu XG |
|
Evidence
|
Phenotypic analyses were performed to evaluate HBsAg production, replication capacity, and drug-induced viral inhibition of patient-derived drug-resistant mutants with or without the coexistence of sA159V.
|
|
|
HBV Mutation Detail Information