HBV Mutation Detail Information

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Mutation Information

Mutation Site	A1762T
Mutation Type	Nucleotide level
Gene/Protein/Region Type	BCP
Combined Mutation	bcp.G1764A+bcp.A1762T
Country	Italy

Literature Information

PubMed PMID	12010505
Disease	Chronic hepatitis B
Published Year	2002
Journal	Journal of viral hepatitis
Title	Sequential analysis of hepatitis B virus core promoter and precore regions in cancer survivor patients with chronic hepatitis B before, during and after interferon treatment.
Author	Zampino R,Marrone A,Cirillo G,del Giudice EM,Utili R,Karayiannis P,Liang TJ,Ruggiero G
Evidence	Five of the six (83%) responders displayed the double CP mutation A1762T/G1764A always in association with a T1753C change. None of the nonresponders showed these mutations at any time point. The G1896A change creating the PC stop codon mutation was never detected in any of the patients.

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Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation