|
Mutation Information
|
Mutation Site
|
A1762T |
|
Mutation Type
|
Nucleotide level |
|
Gene/Protein/Region Type
|
BCP |
|
Combined Mutation
|
bcp.G1764A+bcp.A1762T |
|
Genotype/Subtype
|
A;D |
|
Relevant Drug
|
lamivudine (LAM) |
Literature Information
|
PubMed PMID
|
14752824
|
|
Disease
|
Chronic hepatitis B
|
|
Published Year
|
2004 |
|
Journal
|
Hepatology (Baltimore, Md.) |
|
Title
|
Identification of HBV DNA sequences that are predictive of response to lamivudine therapy. |
|
Author
|
Ciancio A,Smedile A,Rizzetto M,Lagget M,Gerin J,Korba B |
|
Evidence
|
Reversions of precore mutations A1762T/G1764A and G1896A were observed in 29% and 25% of patients, respectively, but none became HBeAg-positive.
|
|
|
HBV Mutation Detail Information