HBV Mutation Detail Information

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Mutation Information

Mutation Site	A1762T
Mutation Type	Nucleotide level
Gene/Protein/Region Type	BCP
Combined Mutation	bcp.G1764A+bcp.A1762T
Country	Japan

Literature Information

PubMed PMID	16871568
Disease	Acute hepatitis B
Published Year	2006
Journal	Hepatology (Baltimore, Md.)
Title	Influence of genotypes and precore mutations on fulminant or chronic outcome of acute hepatitis B virus infection.
Author	Ozasa A,Tanaka Y,Orito E,Sugiyama M,Kang JH,Hige S,Kuramitsu T,Suzuki K,Tanaka E,Okada S,Tokita H,Asahina Y,Inoue K,Kakumu S,Okanoue T,Murawaki Y,Hino K,Onji M,Yatsuhashi H,Sakugawa H,Miyakawa Y,Ueda R,Mizokami M
Evidence	Precore (G1896A) and core-promoter (A1762T/G1764A) mutations were more frequent in patients with fulminant than acute self-limited hepatitis (53% vs. 9% and 50% vs. 17%, P < .0001 for both).

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Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation