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Mutation Information
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Mutation Site
|
A1762T |
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Mutation Type
|
Nucleotide level |
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Gene/Protein/Region Type
|
BCP |
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Genotype/Subtype
|
C |
|
Country
|
Japan |
Literature Information
|
PubMed PMID
|
20932594
|
|
Disease
|
HBV infection
|
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Published Year
|
2011 |
|
Journal
|
Journal of hepatology |
|
Title
|
Evolution of hepatitis B genotype C viral quasi-species during hepatitis B e antigen seroconversion. |
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Author
|
Wu S,Imazeki F,Kurbanov F,Fukai K,Arai M,Kanda T,Yonemitsu Y,Tanaka Y,Mizokami M,Yokosuka O |
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Evidence
|
Parsimony-based estimation of the direction of sequence change between descendants and ancestors before HBeAg seroconversion, revealed higher frequencies of transversional A to T substitution in seroconverters (0.06 vs. 0.02, p = 0.0036) that coincided with the dynamics of quasi-species possessing A1762T mutation.
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