HBV Mutation Detail Information

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Mutation Information
Mutation Site A1762T
Mutation Type Nucleotide level
Gene/Protein/Region Type BCP
Genotype/Subtype C
Country Japan
Literature Information
PubMed PMID 20932594
Disease HBV infection
Published Year 2011
Journal Journal of hepatology
Title Evolution of hepatitis B genotype C viral quasi-species during hepatitis B e antigen seroconversion.
Author Wu S,Imazeki F,Kurbanov F,Fukai K,Arai M,Kanda T,Yonemitsu Y,Tanaka Y,Mizokami M,Yokosuka O
Evidence Parsimony-based estimation of the direction of sequence change between descendants and ancestors before HBeAg seroconversion, revealed higher frequencies of transversional A to T substitution in seroconverters (0.06 vs. 0.02, p = 0.0036) that coincided with the dynamics of quasi-species possessing A1762T mutation.

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation