|
Mutation Information
|
Mutation Site
|
A1762T |
|
Mutation Type
|
Nucleotide level |
|
Gene/Protein/Region Type
|
BCP |
|
Combined Mutation
|
bcp.G1764A+bcp.A1762T |
|
Nucleotide_Mutation
|
K130M |
|
Genotype/Subtype
|
D |
|
Country
|
India |
Literature Information
|
PubMed PMID
|
25333524
|
|
Disease
|
Hepatocellular carcinoma;
Liver cirrhosis
|
|
Published Year
|
2014 |
|
Journal
|
PloS one |
|
Title
|
Novel point and combo-mutations in the genome of hepatitis B virus-genotype D: characterization and impact on liver disease progression to hepatocellular carcinoma. |
|
Author
|
Datta S,Ghosh A,Dasgupta D,Ghosh A,Roychoudhury S,Roy G,Das S,Das K,Gupta S,Basu K,Basu A,Datta S,Chowdhury A,Banerjee S |
|
Evidence
|
Furthermore, the effect of individual mutation was magnified by the combination with A1762T/G1764A in HCC pathogenesis.
|
|
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HBV Mutation Detail Information