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Mutation Information
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Mutation Site
|
A1762T |
|
Mutation Type
|
Nucleotide level |
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Gene/Protein/Region Type
|
BCP |
|
Genotype/Subtype
|
B;C |
|
Country
|
China |
Literature Information
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PubMed PMID
|
26202756
|
|
Disease
|
Acute on chronic liver failure
|
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Published Year
|
2014 |
|
Journal
|
Hepatology international |
|
Title
|
Hepatitis B virus genotype B and mutations in basal core promoter and pre-core/core genes associated with acute-on-chronic liver failure: a multicenter cross-sectional study in China. |
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Author
|
Yang G,Han M,Chen F,Xu Y,Chen E,Wang X,Liu Y,Sun J,Hou J,Ning Q,Wang Z |
|
Evidence
|
The A1762T/G1764A, A1846T and G1896A mutations were significantly more common in HB-ACLF patients infected with either genotype B or C as compared with CHB-M, whereas the C1913A/G and A2159G mutations were more associated with HB-ACLF in genotype C patients.
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