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Mutation Information
|
Mutation Site
|
A1762T |
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Mutation Type
|
Nucleotide level |
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Gene/Protein/Region Type
|
BCP |
|
Country
|
China |
Literature Information
|
PubMed PMID
|
27779207
|
|
Disease
|
Hepatocellular carcinoma
|
|
Published Year
|
2016 |
|
Journal
|
Scientific reports |
|
Title
|
HBV core promoter mutations and AKT upregulate S-phase kinase-associated protein 2 to promote postoperative hepatocellular carcinoma progression. |
|
Author
|
Chen L,Gu L,Gu Y,Wang H,Deng M,Stamataki Z,Oo YH,Huang Y |
|
Evidence
|
Results showed double mutation A1762T/G1764A (TA) combined with other mutation(s) (TACO) in HBV genome and phosphorylated AKT (pAKT) were more common in PHCC than BHCC.
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