|
Mutation Information
|
Mutation Site
|
A1762T |
|
Mutation Type
|
Nucleotide level |
|
Gene/Protein/Region Type
|
C Promoter |
|
Combined Mutation
|
c promoter.G1764A+c promoter.A1762T |
|
Genotype/Subtype
|
A;C |
|
Country
|
Korea |
Literature Information
|
PubMed PMID
|
28373061
|
|
Clinical information
|
Yes
|
|
Disease
|
Liver cirrhosis;
Hepatocellular carcinoma
|
|
Published Year
|
2017 |
|
Journal
|
Virus research |
|
Title
|
Sequence analysis and functional characterization of full-length hepatitis B virus genomes from Korean cirrhotic patients with or without liver cancer. |
|
Author
|
Zhou H,Gewaily D,Ahn SH,Preskill C,Wang Y,Zong L,Zhang J,Han KH,Wands J,Li J,Tong S |
|
Evidence
|
While A1762T/G1764A core promoter mutations were highly prevalent in both groups, the G1896A precore mutation to abolish hepatitis B e antigen (HBeAg) expression was more common in HCC clones (55% vs.
|
|
|
HBV Mutation Detail Information