|
Mutation Information
|
Mutation Site
|
A1762T |
|
Mutation Type
|
Nucleotide level |
|
Gene/Protein/Region Type
|
BCP |
|
Combined Mutation
|
bcp.G1764A+bcp.A1762T |
|
Country
|
China |
Literature Information
|
PubMed PMID
|
29065883
|
|
Clinical information
|
Yes
|
|
Disease
|
Acute on chronic liver failure
|
|
Published Year
|
2017 |
|
Journal
|
Virology journal |
|
Title
|
Chronic hepatitis B carriers with acute on chronic liver failure show increased HBV surface gene mutations, including immune escape variants. |
|
Author
|
Gao S,Joshi SS,Osiowy C,Chen Y,Coffin CS,Duan ZP |
|
Evidence
|
Clonal sequencing of PCR-amplified HBV P/S and BCP/PC gene fragments was done and HBV diversity, frequency of immune escape (IE) and drug resistance (DR) mutations and mutations in BCP/PC gene (G1896A and A1762T/G1764A), were compared between each group.
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HBV Mutation Detail Information