|
Mutation Information
|
Mutation Site
|
A1762T |
|
Mutation Type
|
Nucleotide level |
|
Gene/Protein/Region Type
|
BCP |
|
Combined Mutation
|
bcp.G1764A+bcp.A1762T |
|
Genotype/Subtype
|
F |
Literature Information
|
PubMed PMID
|
29096158
|
|
Published Year
|
2018 |
|
Journal
|
Virology |
|
Title
|
Human hepatocytes apoptosis induced by replication of hepatitis B virus subgenotypes F1b and F4: Role of basal core promoter and preCore mutations. |
|
Author
|
Elizalde MM,Sevic I,González López Ledesma MM,Campos RH,Barbini L,Flichman DM |
|
Evidence
|
The BCPdm (A1762T/G1764A) and preCore (G1896A) mutants induced higher levels of apoptosis than the wt virus.
|
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