|
Mutation Information
|
Mutation Site
|
A1814C |
|
Mutation Type
|
Nucleotide level |
|
Gene/Protein/Region Type
|
PreC |
|
Combined Mutation
|
prec.C1816T+prec.A1814C |
|
Genotype/Subtype
|
A;D |
|
Viral Reference
|
X75657;
X72702;
X70185 |
|
Country
|
Ethiopia |
Literature Information
|
PubMed PMID
|
29408943
|
|
Disease
|
HBV-HIV coinfection;
HBV associated liver disease;
HBV infection
|
|
Published Year
|
2018 |
|
Journal
|
PloS one |
|
Title
|
Analysis of HBV basal core promoter/precore gene variability in patients with HBV drug resistance and HIV co-infection in Northwest Ethiopia. |
|
Author
|
Belyhun Y,Liebert UG,Maier M |
|
Evidence
|
Among the major mutant variants detected, double BCP mutations (A1762T/G1764A) (25.9%), Kozak sequences mutations (nt1809-1812) (51.7%) and the classical PC mutations such as A1814C/C1816T (15.4%), G1896A (25.2%) and G1862T (44.8%) were predominant mutant variants.
|
|
|
HBV Mutation Detail Information