|
Mutation Information
|
Mutation Site
|
A181S |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Combined Mutation
|
rt.M204V+rt.S202G+rt.A181S+rt.L180M;rt.N236T+rt.A181S |
|
Genotype/Subtype
|
B;C |
|
Relevant Drug
|
adefovir (ADV);lamivudine (LAM);entecavir (ETV);tenofovir (TDF) |
|
Country
|
China |
Literature Information
|
PubMed PMID
|
25132017
|
|
Disease
|
HBV infection
|
|
Published Year
|
2015 |
|
Journal
|
Journal of viral hepatitis |
|
Title
|
The rtA181S mutation of hepatitis B virus primarily confers resistance to adefovir dipivoxil. |
|
Author
|
Liu Y,Li X,Xin S,Xu Z,Chen R,Yang J,Liu L,Wong VW,Yang D,Chan HL,Xu D |
|
Evidence
|
The rtA181S mutation of hepatitis B virus primarily confers resistance to adefovir dipivoxil.
|
|
|