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HBV Mutation Detail Information

> A181T Search Result


Mutation Information
Mutation Site A181T
Mutation Type Amino acid level
Gene/Protein/Region Type RT
Relevant Drug lamivudine (LAM)
Literature Information
PubMed PMID 15720530
Disease Chronic hepatitis B
Published Year 2005
Journal Journal of viral hepatitis
Title Long-term follow-up of chronic hepatitis B after the emergence of mutations in the hepatitis B virus polymerase region.
Author Natsuizaka M,Hige S,Ono Y,Ogawa K,Nakanishi M,Chuma M,Yoshida S,Asaka M
Evidence The first mutation patterns of the LLAQ motif in domain B were LMAQ (rtL180M) in five patients (83.3%) and LLTQ (rtA181T) in one patient (16.7%), and those of the YMDD motif in domain C were YIDD (rtM204I) in 10 patients (76.9%) and YVDD (rtM204V) in three patients (23.1%).
Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation