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Mutation Information
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Mutation Site
|
A181T |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Combined Mutation
|
rt.N236T+rt.A181T |
|
Relevant Drug
|
adefovir (ADV) |
Literature Information
|
PubMed PMID
|
17591025
|
|
Published Year
|
2007 |
|
Journal
|
Antiviral therapy |
|
Title
|
In vitro susceptibility of adefovir-associated hepatitis B virus polymerase mutations to other antiviral agents. |
|
Author
|
Qi X,Xiong S,Yang H,Miller M,Delaney WE 4th |
|
Evidence
|
We generated five stable cell line that each expressed one of the following HBV mutants: rtN236T, rtA181V, rtA181V + rtN236T, rtA181T + rtN236T and rtA181T.
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HBV Mutation Detail Information