|
Mutation Information
|
Mutation Site
|
A181T |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Relevant Drug
|
lamivudine (LAM);adefovir (ADV) |
|
Country
|
USA |
Literature Information
|
PubMed PMID
|
22510694
|
|
Disease
|
HBV infection
|
|
Published Year
|
2012 |
|
Journal
|
Nature communications |
|
Title
|
Convergence and coevolution of hepatitis B virus drug resistance. |
|
Author
|
Thai H,Campo DS,Lara J,Dimitrova Z,Ramachandran S,Xia G,Ganova-Raeva L,Teo CG,Lok A,Khudyakov Y |
|
Evidence
|
Nine of ten HBV variants containing ATC (Fig. 1) harboured additional substitution rtA181T that also confers decreased susceptibility to lamivudine and adefovir10.
|
|
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HBV Mutation Detail Information