|
Mutation Information
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Mutation Site
|
A181T |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Relevant Drug
|
lamivudine (LAM);adefovir (ADV);telbivudine (LDT);entecavir (ETV);tenofovir (TDF) |
Literature Information
|
PubMed PMID
|
24175223
|
|
Published Year
|
2012 |
|
Journal
|
World journal of virology |
|
Title
|
Antiviral treatment to prevent chronic hepatitis B or C-related hepatocellular carcinoma. |
|
Author
|
Chen LP,Zhao J,Du Y,Han YF,Su T,Zhang HW,Cao GW |
|
Evidence
|
Of the NA resistance-associated mutants, A181T mutant significantly increases the risk of HCC development during the subsequent course of NA therapy.
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|
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HBV Mutation Detail Information