HBV Mutation Detail Information

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Mutation Information
Mutation Site A181T
Mutation Type Amino acid level
Gene/Protein/Region Type RT
Relevant Drug adefovir dipivoxil (ADV)
Country India
Literature Information
PubMed PMID 28139541
Disease Chronic hepatitis B
Published Year 2016
Journal The Indian journal of medical research
Title Comparative evaluation of long-term monotherapies & combination therapies in patients with chronic hepatitis B: A pilot study.
Author Srivastava M,Singh N,Dixit VK,Nath G,Jain AK
Evidence VBT on ADV monotherapy was noted in eight patients (33.3%), rtA181T and rtN236T mutants were detected alone in 8.1 and 8.3 per cent in the conserved regions B and D of rt region of HBV polymerase gene, respectively.

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation