|
Mutation Information
|
Mutation Site
|
A181T |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Amino acid_Mutation
|
G670A |
|
Relevant Drug
|
adefovir (ADV) |
|
Country
|
china |
Literature Information
|
PubMed PMID
|
32840739
|
|
Disease
|
Chronic hepatitis B
|
|
Published Year
|
2020 |
|
Journal
|
Virus genes |
|
Title
|
An antiviral drug-resistant mutant of hepatitis B virus with high replication capacity in association with a large in-frame deletion in the preS1 region of viral surface gene. |
|
Author
|
Wang T,Qin Y,Zhang J,Li X,Tong S,Zhao W,Zhang J |
|
Evidence
|
Mutation(s) in the polymerase gene responsible for ADV resistance included rtA181T (all clones) and rtN236T (four clones).
|
|
|
HBV Mutation Detail Information