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Mutation Information
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Mutation Site
|
A2191C |
|
Mutation Type
|
Nucleotide level |
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Gene/Protein/Region Type
|
C |
|
Nucleotide_Mutation
|
I97L |
|
Immune Escape
|
Y |
Literature Information
|
PubMed PMID
|
12414948
|
|
Published Year
|
2002 |
|
Journal
|
Journal of virology |
|
Title
|
Replication advantage and host factor-independent phenotypes attributable to a common naturally occurring capsid mutation (I97L) in human hepatitis B virus. |
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Author
|
Suk FM,Lin MH,Newman M,Pan S,Chen SH,Liu JD,Shih C |
|
Evidence
|
We created mutant I97F (A2191T) and compared its replication with that of wild-type HBV and mutant I97L (A2191C) in both HepG2 and Huh7 cells.
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