HBV Mutation Detail Information

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Mutation Information

Mutation Site	A79G
Mutation Type	Nucleotide level
Gene/Protein/Region Type	P
Nucleotide_Mutation	N332D

Literature Information

PubMed PMID	27473751
Published Year	2016
Journal	The Journal of general virology
Title	Enhanced pregenomic RNA levels and lowered precore mRNA transcription efficiency in a genotype A hepatitis B virus genome with C1766T and T1768A mutations obtained from a fulminant hepatitis patient.
Author	Nishizawa T,Hoshino T,Naganuma A,Kobayashi T,Nagashima S,Takahashi M,Takagi H,Okamoto H
Evidence	A mutation (A to G) found at nt 79 in the FH genome (Fig. 1a) changes Asn to Asp at amino acid residue 332 of the P gene product, but not Gly at amino acid residue 30 of the overlapping preS2 protein, a mutation that was found in a chronic hepatitis patient in Maranhão state, Northeast Brazil (AFR43422) (Barros et al., 2014) and a symptom-free blood donor in the USA (AFH87373) (Delwart et al., 2012).

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Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation