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HBV Mutation Detail Information

> C144K Search Result


Mutation Information
Mutation Site C144K
Mutation Type Amino acid level
Gene/Protein/Region Type C
Literature Information
PubMed PMID 10573159
Published Year 1999
Journal The Journal of general virology
Title Hepatitis B virus maturation is affected by the incorporation of core proteins having a C-terminal substitution of arginine or lysine stretches.
Author Hui EK,Chen KL,Lo SJ
Evidence In this study, two hepatitis B virus (HBV) core mutants (C144Arg and C144Lys) in which the C-terminal SPRRR (Ser-Pro-Arg-Arg-Arg) motif was replaced by a stretch of arginine or lysine residues were generated to test their role in pregenome encapsidation and virus maturation.
Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation