HBV Mutation Detail Information

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Mutation Information

Mutation Site	C1766G
Mutation Type	Nucleotide level
Gene/Protein/Region Type	BCP
Genotype/Subtype	D
Viral Reference	X02763
Country	Iran

Literature Information

PubMed PMID	16099903
Disease	Chronic hepatitis B
Published Year	2005
Journal	The Journal of general virology
Title	T1764G1766 core promoter double mutants are restricted to Hepatitis B virus strains with an A1757 and are common in genotype D.
Author	Sendi H,Mehrab-Mohseni M,Zali MR,Norder H,Magnius LO
Evidence	The most common muta- tion was C1766G (38 % patients), followed by G1764A (32 %), G1764T (31 %), A1762T (29 %) and T1753C (20 %), with no significant difference in frequencies between e-CHB patients and ASCs; a G1757A substitution was found in 71 % of the strains and was considered to be a genotype D wild-type substitution.

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Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation