HBV Mutation Detail Information

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Mutation Information

Mutation Site	C1766T
Mutation Type	Nucleotide level
Gene/Protein/Region Type	BCP

Literature Information

PubMed PMID	19327810
Published Year	2009
Journal	Virology
Title	Chimeric constructs between two hepatitis B virus genomes confirm transcriptional impact of core promoter mutations and reveal multiple effects of core gene mutations.
Author	Tsai A,Kawai S,Kwei K,Gewaily D,Hutter A,Tong DR,Li J,Wands JR,Tong S
Evidence	Introduction of its T1753C, A1762T, G1764A, and C1766T core promoter mutations into the 2A genome greatly enhanced genome replication and suppressed HBeAg expression.

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Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation