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Mutation Information
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Mutation Site
|
C1858T |
|
Mutation Type
|
Nucleotide level |
|
Gene/Protein/Region Type
|
BCP |
|
Country
|
Cameroun |
Literature Information
|
PubMed PMID
|
24265811
|
|
Disease
|
HBV infection
|
|
Published Year
|
2013 |
|
Journal
|
PloS one |
|
Title
|
High endemicity and low molecular diversity of hepatitis B virus infections in pregnant women in a rural district of North Cameroon. |
|
Author
|
Ducancelle A,Abgueguen P,Birguel J,Mansour W,Pivert A,Le Guillou-Guillemette H,Sobnangou JJ,Rameau A,Huraux JM,Lunel-Fabiani F |
|
Evidence
|
There was no significant difference in the mutant BCP phenotype distribution between the HBeAg-negative and HBeAg-positive pregnant women: 13/59 (22%) and 48/169 (28.4%) respectively (p=0.8). The C1858T and G1757A substitutions were found in 226/228 (99.1%) and 189/228 patients (82.8%) respectively.
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