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Mutation Information
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Mutation Site
|
C185S |
|
Mutation Type
|
Amino acid level |
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Gene/Protein/Region Type
|
L1 |
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Genotype/Subtype
|
HPV16 |
Literature Information
|
PubMed PMID
|
21811610
|
|
Published Year
|
2011 |
|
Journal
|
PloS one |
|
Title
|
Differentiation-dependent interpentameric disulfide bond stabilizes native human papillomavirus type 16. |
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Author
|
Conway MJ,Cruz L,Alam S,Christensen ND,Meyers C |
|
Evidence
|
Specifically, the C175S substitution severely undermined wild-type titers of the virus within both 10 and 20-day tissue, while C428S, C185S, and C175,185S substitutions severely undermined wild-type titers only within 20-day tissue.
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