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Mutation Information
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Mutation Site
|
C228A |
|
Mutation Type
|
Amino acid level |
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Gene/Protein/Region Type
|
Env |
Literature Information
|
PubMed PMID
|
18480461
|
|
Published Year
|
2008 |
|
Journal
|
Journal of virology |
|
Title
|
Intersubunit disulfide isomerization controls membrane fusion of human T-cell leukemia virus Env. |
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Author
|
Li K,Zhang S,Kronqvist M,Wallin M,Ekström M,Derse D,Garoff H |
|
Evidence
|
We introduced the C225A and C228A mutations into Env and found that the former but not the latter mutant matured into covalently linked SU-TM complexes in transfected cells.
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