|
Mutation Information
|
Mutation Site
|
C24G |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
E7 |
|
Genotype/Subtype
|
HPV16 |
Literature Information
|
PubMed PMID
|
11543887
|
|
Published Year
|
2001 |
|
Journal
|
Journal of virological methods |
|
Title
|
Determination of the binding affinity of different human papillomavirus E7 proteins for the tumour suppressor pRb by a plate-binding assay. |
|
Author
|
Dong WL,Caldeira S,Sehr P,Pawlita M,Tommasino M |
|
Evidence
|
Point mutation C24G in the high affinity pRb-binding domain of HPV16 E7 results in a 3-fold affinity reduction.
|
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