HPV Mutation Detail Information

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Mutation Information

Mutation Site	C520T
Mutation Type	Nucleotide level
Gene/Protein/Region Type	E6
Genotype/Subtype	HPV31
Viral Reference	NC_001527
Country	China

Literature Information

PubMed PMID	24901850
Disease	HPV infection
Published Year	2014
Journal	PloS one
Title	The distribution and common amino acid polymorphisms of human papillomavirus (HPV)-31 variants in 2700 women from Northern China.
Author	Liu M,He Z,Xi L,Li J,Liu F,Liu Y,Pan Y,Ning T,Guo C,Xu R,Zhang L,Cai H,Ke Y
Evidence	Five previously identified non-synonymous nucleotide alternations C285T (5/14), C520T (5/14), C626T (9/14), G695A (5/14) and A743G (14/14) were frequently detected (>25%) [7], [13], leading to amino acid changes H60Y, A138V in E6 protein of C variants, H23Y in E7 protein of A variants, E46K in E7 protein of C variants, and K62E in E7 protein of both A and C variants identified in China, respectively.

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Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation