|
Mutation Information
|
Mutation Site
|
C61R |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
C |
|
Genotype/Subtype
|
A;C;F |
Literature Information
|
PubMed PMID
|
15661154
|
|
Disease
|
HBV infection
|
|
Published Year
|
2005 |
|
Journal
|
Virology |
|
Title
|
Effect of mutating the two cysteines required for HBe antigenicity on hepatitis B virus DNA replication and virion secretion. |
|
Author
|
Bang G,Kim KH,Guarnieri M,Zoulim F,Kawai S,Li J,Wands J,Tong S |
|
Evidence
|
Consistent with the detection of C61R genome from a patient serum, secretion block of the C61R mutant could be overcome by co-expression of wild-type core protein.
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