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Mutation Information
|
Mutation Site
|
C632T |
|
Mutation Type
|
Nucleotide level |
|
Gene/Protein/Region Type
|
E7 |
|
Nucleotide_Mutation
|
T20I |
|
Genotype/Subtype
|
HPV58 |
Literature Information
|
PubMed PMID
|
33155930
|
|
Published Year
|
2020 |
|
Journal
|
Anti-cancer agents in medicinal chemistry |
|
Title
|
Human Papillomavirus E7 Oncoprotein Promotes Proliferation and Migration through the Transcription Factor E2F1 in Cervical Cancer Cells. |
|
Author
|
Tian S,Zhang L,Li Y,Cao D,Quan S,Guo Y,Yang X,Yang T |
|
Evidence
|
OBJECTIVE: This study aimed to determine whether the HPV58 E7 T20I (C632T) variant promotes the malignant behavior of cervical cancer cells and the underlying mechanism of the HR-HPV E7 oncoprotein involved in the development of cervical cancer.
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HPV Mutation Detail Information