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Mutation Information
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Mutation Site
|
C640T |
|
Mutation Type
|
Nucleotide level |
|
Gene/Protein/Region Type
|
E7 |
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Genotype/Subtype
|
HPV18 |
|
Viral Reference
|
NC_001357.1
|
|
Country
|
China |
Literature Information
|
PubMed PMID
|
23451059
|
|
Disease
|
Cervical carcinoma
|
|
Published Year
|
2013 |
|
Journal
|
PloS one |
|
Title
|
Sequence variation analysis of HPV-18 isolates in southwest China. |
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Author
|
Shen M,Ding X,Li T,Chen G,Zhou X |
|
Evidence
|
DNA sequence analysis of the HPV-18 E7 region revealed two variations, both of which occurred only once and in the same specimen: a C to T transition at nt640, which did not result in an AA change (Fig. 1G), and an A to G transition at nt864, leading to a N92S AA substitution (n = 1, 1.79%) (Fig. 1H).
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HPV Mutation Detail Information