|
Mutation Information
|
Mutation Site
|
C712A |
|
Mutation Type
|
Nucleotide level |
|
Gene/Protein/Region Type
|
E7 |
|
Combined Mutation
|
e6.A131G+e7.C712A |
|
Genotype/Subtype
|
HPV16 |
Literature Information
|
PubMed PMID
|
15006625
|
|
Disease
|
Squamous-cell carcinoma;
Head and neck carcinoma
|
|
Published Year
|
2004 |
|
Journal
|
Oral oncology |
|
Title
|
Human papillomavirus type 16 E6 and E7 genotypes in head-and-neck carcinomas. |
|
Author
|
Hoffmann M,Lohrey C,Hunziker A,Kahn T,Schwarz E |
|
Evidence
|
Sequence analysis of the E6-E7 segments revealed three different HPV16 E6-E7 genotypes: the HPV16 prototype (6 of 21 cases), the E6 variant T350G (8 of 21 cases), and the E6-E7 variant A131G/C712A (7 of 21 cases).
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HPV Mutation Detail Information