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Mutation Information
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Mutation Site
|
C95E |
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Mutation Type
|
Amino acid level |
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Gene/Protein/Region Type
|
BMRF1 |
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Viral Reference
|
V01555.2
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Literature Information
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PubMed PMID
|
19801550
|
|
Published Year
|
2009 |
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Journal
|
The Journal of biological chemistry |
|
Title
|
Crystal structure of epstein-barr virus DNA polymerase processivity factor BMRF1. |
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Author
|
Murayama K,Nakayama S,Kato-Murayama M,Akasaka R,Ohbayashi N,Kamewari-Hayami Y,Terada T,Shirouzu M,Tsurumi T,Yokoyama S |
|
Evidence
|
The C95E mutant, which disrupts dimer formation, lacked DNA binding activity, indicating that dimer formation is required for DNA binding.
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EBV Mutation Detail Information