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Mutation Information
|
Mutation Site
|
D134E |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Viral Reference
|
X01587
|
|
Country
|
China |
Literature Information
|
PubMed PMID
|
22882650
|
|
Disease
|
HBV infection
|
|
Published Year
|
2012 |
|
Journal
|
Liver international : official journal of the International Association for the Study of the Liver |
|
Title
|
Prevalence and significance of Hepatitis B reverse transcriptase mutants in different disease stages of untreated patients. |
|
Author
|
Zheng J,Zeng Z,Zhang D,Yu Y,Wang F,Pan CQ |
|
Evidence
|
And the rtD134E/G/N/S mutations were also higher in chronic hepatitis B patients (22/100, 22.0%) and cirrhotic patients 21.0%) than that in hepatocellular carcinoma patients (10/100, 10.0%, P=0.021 and P=0.032, respectively).
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