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Mutation Information
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Mutation Site
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D44N |
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Mutation Type
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Amino acid level |
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Gene/Protein/Region Type
|
Small T |
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Country
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America |
Literature Information
|
PubMed PMID
|
21841310
|
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Disease
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Merkel cell carcinoma
|
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Published Year
|
2011 |
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Journal
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The Journal of clinical investigation |
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Title
|
Human Merkel cell polyomavirus small T antigen is an oncoprotein targeting the 4E-BP1 translation regulator. |
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Author
|
Shuda M,Kwun HJ,Feng H,Chang Y,Moore PS |
|
Evidence
|
We also examined an sT aspartate-to-asparagine substitution in the exon 1–encoded DnaJ domain, sT.D44N, that eliminates Hsc70 binding to MCV LT
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MCV Mutation Detail Information