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Mutation Information
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Mutation Site
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D60E |
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Mutation Type
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Amino acid level |
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Gene/Protein/Region Type
|
PR |
Literature Information
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PubMed PMID
|
31409143
|
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Published Year
|
2019 |
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Journal
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Journal of enzyme inhibition and medicinal chemistry |
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Title
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Kinetic and thermodynamic characterisation of HIV-protease inhibitors against E35D↑G↑S mutant in the South African HIV-1 subtype C protease. |
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Author
|
Maseko S,Padayachee E,Maphumulo S,Govender T,Sayed Y,Maguire G,Lin J,Naicker T,Baijnath S,Gerhardus KH |
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Evidence
|
The mutant has five mutations, E35D, two insertions, position 36 (G and S), and D60E.
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