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Mutation Information
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Mutation Site
|
D64E |
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Mutation Type
|
Amino acid level |
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Gene/Protein/Region Type
|
IN |
Literature Information
|
PubMed PMID
|
19014595
|
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Published Year
|
2008 |
|
Journal
|
Retrovirology |
|
Title
|
Contribution of the C-terminal region within the catalytic core domain of HIV-1 integrase to yeast lethality, chromatin binding and viral replication. |
|
Author
|
Xu Z,Zheng Y,Ao Z,Clement M,Mouland AJ,Kalpana GV,Belhumeur P,Cohen EA,Yao X |
|
Evidence
|
Furthermore, our data also indicated that this replication defect was partially complemented by the IN class I catalytic mutant D64E.
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HIV Mutation Detail Information