|
Mutation Information
|
Mutation Site
|
E138A |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Relevant Drug
|
efavirenz (EFV);rilpivirine (RPV) |
|
Country
|
China |
Literature Information
|
PubMed PMID
|
32873064
|
|
Disease
|
HIV infection/AIDS
|
|
Published Year
|
2021 |
|
Journal
|
AIDS research and human retroviruses |
|
Title
|
Genetic Characteristics of HIV-1 CRF12_BF First Identified in Guangdong Province, China. |
|
Author
|
Lan Y,He X,Xin R,Li L,Huang X,Deng X,Tang X,Jia W,Cai W,Hu F |
|
Evidence
|
Additionally, this CRF12_BF strain was confirmed to contain the non-nucleoside reverse transcriptase inhibitor mutation E138A associated with potential low-level resistance against efavirenz and low-level resistance against rilpivirine by the Stanford University HIV Drug Resistance Database program.
|
|
|
HIV Mutation Detail Information