HIV Mutation Detail Information

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Mutation Information

Mutation Site	E138K
Mutation Type	Amino acid level
Gene/Protein/Region Type	RT
Relevant Drug	NNRTIs
Country	Portuguese

Literature Information

PubMed PMID	33143301
Disease	HIV infection/AIDS
Published Year	2020
Journal	Viruses
Title	Increasing Prevalence of HIV-1 Transmitted Drug Resistance in Portugal: Implications for First Line Treatment Recommendations.
Author	Pingarilho M,Pimentel V,Diogo I,Fernandes S,Miranda M,Pineda-Pena A,Libin P,Theys K,Martins MRO,Vandamme AM,Camacho R,Gomes P,Abecasis A
Evidence	When considering E138K mutation, TDR increased from 9.4% (95%CI: 8.8-10.1) to 9.5% (95%CI: 8.9-1.0%), while NNRTIs TDR increased from 5.0% (95%CI: 4.5-5.5%) to 5.1% (95%CI: 4.6-5.7%).

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation