|
Mutation Information
|
Mutation Site
|
E54A |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
Vif |
|
Combined Mutation
|
vif.E54A+vif.S53A |
Literature Information
|
PubMed PMID
|
28302150
|
|
Published Year
|
2017 |
|
Journal
|
Retrovirology |
|
Title
|
Identification of a tripartite interaction between the N-terminus of HIV-1 Vif and CBFβ that is critical for Vif function. |
|
Author
|
Desimmie BA,Smith JL,Matsuo H,Hu WS,Pathak VK |
|
Evidence
|
Mutant E45A-S46A, T47-N48A, S53A-E54A, V55A-H56A, and I57A-P58A showed significantly lower binding than WT Vif (Fig. 1c, d; values indicated in green).
|
|
|
HIV Mutation Detail Information