HBV Mutation Detail Information

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Mutation Information

Mutation Site	F23Y
Mutation Type	Amino acid level
Gene/Protein/Region Type	C
Genotype/Subtype	A
Viral Reference	X02763
Country	Asia‐Pacific;Europe

Literature Information

PubMed PMID	32579776
Disease	Chronic hepatitis B
Published Year	2020
Journal	Journal of viral hepatitis
Title	Virology analysis of chronic hepatitis B virus-infected patients treated for 28 days with JNJ-56136379 monotherapy.
Author	Verbinnen T,Hodari M,Talloen W,Berke JM,Blue D,Yogaratnam J,Vandenbossche J,Shukla U,De Meyer S,Lenz O
Evidence	Two JNJ‐6379‐treated patients (both HBeAg‐negative, GT‐A and GT‐E, and JNJ‐6379 75 and 150 mg treated, respectively) carried a Y118F baseline polymorphism, while a placebo‐treated patient (HBeAg‐negative, GT‐H) carried a F23Y baseline polymorphism (FC = 6.6 and 5.2, respectively).

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation