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Mutation Information
|
Mutation Site
|
F605W |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
BRLF1 |
Literature Information
|
PubMed PMID
|
19232420
|
|
Published Year
|
2009 |
|
Journal
|
Virology |
|
Title
|
Two phenylalanines in the C-terminus of Epstein-Barr virus Rta protein reciprocally modulate its DNA binding and transactivation function. |
|
Author
|
Chen LW,Raghavan V,Chang PJ,Shedd D,Heston L,Delecluse HJ,Miller G |
|
Evidence
|
The two mutants with aromatic substitutions, F600W/F605W and F600Y/F605Y, both bound DNA weakly.
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EBV Mutation Detail Information